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What is New with Chromium?

We have discussed how Chromium can elevate your mood and lift you out of depression (Chen et al., 2022). We also went over Chromium's role on glucose metabolism, type 2 diabetes, and heart health (Ngala et al., 2018).

Today, I thought to bring up Chromium's ability to create health and at the same time, if not used correctly or in the right form, to cause toxicity in the body. 

There is also a big difference between Trivalent chromium that offers important health benefits and hexavalent chromium which can lead to cancer (Ray & Jankar, 2022). 

Scientific literature is clear that Chromium is essential - excellent mineral in your must have daily supplement as it aids against insulin resistance, over-weight issues, cholesterol, immunity, and much more. 

This excellent review helps you identify the effects of these two very different chromiums, Trivalent and Hexavalent, as well as Chromium's therapeutic uses, adverse effects, and the effect and role in health and well-being. 


Chromium is an essential trace element whose deficiency can cause impairment of glucose tolerance, growth and various biological functions. There are two isotopes of chromium-trivalent chromium and hexavalent chromium. Both the isotopes of chromium have quite different effects on the human body. The objective of this narrative review is to compile the different effects of the two isotopes of chromium and give a comprehensive analysis of the effects of hexavalent and trivalent chromium. Data from various studies across different forums were compared to provide a concrete analysis of the therapeutic and harmful effects of two isotopes of chromium on human health. Chromium plays a vital role in the biological functions of the body. It might be helpful in balancing the glycaemic levels, triglyceride levels and cholesterol levels in the body. Excessive intake of chromium is harmful for health. Overexposure to chromium can lead to carcinogenic effects. Consumption of an insufficient amount of chromium might not be adequate as well. Trivalent chromium can be quite beneficial if taken in proper quantities. Hexavalent chromium can cause cancer. Trivalent chromium is beneficial, while hexavalent chromium is harmful to human health. Article


Yours as always,



  • Chen, J., Kan, M., Ratnasekera, P., Deol, L. K., Thakkar, V., & Davison, K. M. (2022). Blood Chromium Levels and Their Association with Cardiovascular Diseases, Diabetes, and Depression: National Health and Nutrition Examination Survey (NHANES) 2015–2016. Nutrients14(13), 2687. Article
  • Maret, W. (2019). Chromium supplementation in human health, metabolic syndrome, and diabetes. Met. Ions Life Sci, 19, 231-251.
  • Ngala, R. A., Awe, M. A., & Nsiah, P. (2018). The effects of plasma chromium on lipid profile, glucose metabolism and cardiovascular risk in type 2 diabetes mellitus. A case-control study. PLoS One, 13(7), e0197977.
  • Ray, A., & Jankar, J. S. (2022). A Comparative Study of Chromium: Therapeutic Uses and Toxicological Effects on Human Health. Journal of Pharmacology and Pharmacotherapeutics, 0976500X221128646. Article 

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

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Read about our Trivalent Chromium with red beetroot:

Chromium with High Active Beet Root  

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