Probiotics and GI Distress

Dear Friends

A dysbiotic gut is one of the major drivers of chronic inflammation in our body, and as we know chronic inflammation is a major etiological factors in our chronic disease pandemic.

Generally a dysbiotic gut is characterized by a reduced diversity with fewer butyrate-producing Firmacutes and more gram negative pathobionts.  Such dysbiosis has been identified in the contexts of frailty in the elderly (van Tongeren et al., 2005), Crohn's disease (De Cruz et al., 2012), ulcerative colitis (Lepage et al., 2011), obesity (Furet et al., 2010), type-2 diabetes (Burcelin et al., 2011), allergy (Abrahamsson et al., 2012), colorectal cancer (Chen et al., 2012), irritable bowel syndrome (Carroll et al., 2012), non-alcoholic fatty liver disease (Henao-Mejia et al., 2012), and cardiovascular disorders (Karlsson et al., 2012).

The No. 7 Systemic Booster provides 10 different probiotic organisms, their supernatant and ORNs:  A broad diversity of beneficial probiotics, prebiotics, antioxidants and polyphenols strongly supporting a reduction of inflammation and the resolution of dysbiosis.



Potent Phytonutrient– Organic berries, fruits, hardy vegetables, and green leafy vegetables: strawberry, raspberry, blueberry, tart cherry, elderberry, cranberry, apple extract, pineapple, beet, broccoli florets, kale leaves, spinach leaves. BioImmersion Super Blend: Probiotics– Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus reuteri, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium lactic, Bifidobacterium longum, Streptococcus thermophilus and Lactobacillus bulgaricus. Supernatant– probiotic metabolites, and ORNs. Prebiotics– Inulin from Chicory Root along with Fibers- from organic veggies, greens, fruits, and berries. VitalNutriceuticals– Fructo Borate, Vitamin B12, Vitamin D3, Folate, Chromium.

Take one to two teaspoons daily.

References: 

• van Tongeren, S. P., Slaets, J. P., Harmsen, H. J. M., & Welling, G. W. (2005). Fecal microbiota composition and frailty. Applied and environmental microbiology, 71(10), 6438-6442. Article
• De Cruz, P., Prideaux, L., Wagner, J., Ng, S. C., McSweeney, C., Kirkwood, C., ... & Kamm, M. A. (2011). Characterization of the gastrointestinal microbiota in health and inflammatory bowel disease. Inflammatory bowel diseases, 18(2), 372-390. https://doi.org/10.1002/ibd.21751
• Lepage, P., Häsler, R., Spehlmann, M. E., Rehman, A., Zvirbliene, A., Begun, A., ... & Schreiber, S. (2011). Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis. Gastroenterology, 141(1), 227-236. Abstract
• Furet, J. P., Kong, L. C., Tap, J., Poitou, C., Basdevant, A., Bouillot, J. L., ... & Rizkalla, S. (2010). Differential adaptation of human gut microbiota to bariatric surgery–induced weight loss: links with metabolic and low-grade inflammation markers. Diabetes, 59(12), 3049-3057.
• Burcelin, R., Serino, M., Chabo, C., Blasco-Baque, V., & Amar, J. (2011). Gut microbiota and diabetes: from pathogenesis to therapeutic perspective. Acta diabetologica, 48(4), 257-273.
• Abrahamsson, T. R., Jakobsson, H. E., Andersson, A. F., Björkstén, B., Engstrand, L., & Jenmalm, M. C. (2012). Low diversity of the gut microbiota in infants with atopic eczema. Journal of allergy and clinical immunology, 129(2), 434-440.
• Chen, W., Liu, F., Ling, Z., Tong, X., & Xiang, C. (2012). Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer. PloS one, 7(6), e39743.
• Carroll, I. M., Ringel‐Kulka, T., Siddle, J. P., & Ringel, Y. (2012). Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea‐predominant irritable bowel syndrome. Neurogastroenterology & Motility, 24(6), 521-e248.
• Henao-Mejia, J., Elinav, E., Jin, C., Hao, L., Mehal, W. Z., Strowig, T., ... & Camporez, J. P. (2012). Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature, 482(7384), 179-185.
• Karlsson, F. H., Fåk, F., Nookaew, I., Tremaroli, V., Fagerberg, B., Petranovic, D., ... & Nielsen, J. (2012). Symptomatic atherosclerosis is associated with an altered gut metagenome. Nature communications, 3(1), 1-8.

Yours,

Seann and Dohrea Bardell

Green Facts:

Transformation to healthy diets by 2050 will require substantial dietary shifts. Global consumption of fruits, vegetables, nuts and legumes will have to double, and consumption of foods such as red meat and sugar will have to be reduced by more than 50%. A diet rich in plant-based foods and with fewer animal source foods confers both improved health and environmental benefits. (Walter Willett MD, Harvard T.H. Chan School of Public Health, 2019)

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