Osteoporosis Support

Dear Friends

Fractures associated with osteoporosis affect one in three women and one in five men over the age of 50 years, and is largely due to our diet and lack of boron in our soil (Devirian, 2003; Sacco, 2013).

Fructo Borate Complex, Phyto Power, and No. 7 Systemic Booster work together as an intelligent system of nutrients that signals the body to create healthy bone. This is the necessary power found in food.

Therapeutic Food recipe to support the reduction and prevention of Osteoporosis:

• Fructo Borate Complex: 1-2 capsules daily
• Phyto Power: 2 capsules daily
• No. 7 Systemic Booster: 1 tsp daily

Food Science

Macro- and micronutrients contribute to skeletal health by supporting bone matrix production and mineralization.  Of these, calcium, vitamin D and proteins are the most important nutrients for supporting the skeleton (Heaney 1995; Bonjour 2005).

However, because there is very little boron in the soil, Americans and many people in other developed countries, suffer with osteoporosis, even though the dietary intake of calcium and vitamin D is adequate according to the recommended daily allowances (RDA).

Three dietary factors, independent of calcium and/or vitamin D, strongly influence bone and mineral homeostasis and long-term bone health. These are carbohydrate-bound boron, as found in Fructo Borate and No 7. Systemic Booster; polyphenol rich foods as found in Phyto Power and No. 7 Systemic Booster; and prebiotic and probiotic as found in No. 7 Systemic Booster.  No 7 also contains supernatant (rich nutients), vitamin D3, and more (for more on nutrients, see McCabe, 2015; Sacco, 2013).

Fructo Borate Complex: is a complex of calcium ascorbate and carbohydrate bound boron; exactly as it is found in fresh and dried fruits, vegetables and herbs when grown in soils containing boron. Unfortunately, boron is missing in our daily nutrition as industrialized farming has depleted boron from our soil.

A substantial number of metabolic processes in humans and animals are beneficially affected by physiologic amounts of dietary boron.  Boron enhances bone integrity and reduces the risk of osteoporosis by enhancing Vitamin D-3 and the steroid hormones DHEA and testosterone levels in the blood—all commonly found to be increasingly deficient as we reach our senior years (Villareal 2000; Miljkovic 2002; Laird 2010; Sinnesaelo 2011).

Miljkovic’s research found one months supplementation with fructo-borate (as formulated in our Fructo Borate Complex) increased blood levels of D-3 by 19.6%, testosterone by 29.5% and DHEA-S levels by 56% (Miljkovic 2002).

Sinnesaelo’s reseach demonstrates that testosterone is an important hormone for both bone gain and maintenance in men.  Hypogonodal men have accelerated bone turnover (Sinnesaelo 2011).

Villareal concluded that DHEA replacement in those elderly women and men who have very low serum DHEA levels can partially reverse age-related changes is BMD (Villareal 2000).

Laird and researchers found that Vitamin D alone and in combination with calcium appears to have a clear significant effect on bone mineral density (BMD) (Laird 2010).

Phyto Power:  contains three species of wildcrafted Alaskan Rosehips (the whole fruit and seeds), four species of wildcrafted dandelions (aerial parts 90% w/w, roots 10% w/w and flower), and four species of wildcrafted blueberry (fruit >95% w/w and leave and stems < 5% w/w).

Alaska wild berries range from 3 to 10 times higher in phytonutrients (such as carotenoids, catechins, flavonoids and other polyphenols) than those grown in the lower latitudes of the United States (Dinstel, 2013).

High levels of the carotenoid lycopene are found in the Alaska rosehip. Lycopene has gained attention for its strong antioxidative capabilities and for its potential to play a protective role against a number of chronic diseases, including osteoporosis (Rao, 2007).

Epidemiological data using various adult populations have demonstrated a positive relationship between the intake levels or serum levels of lycopene and bone mass, bone turnover and/or fracture risk (Sahni, 2009).

Epidemiological studies have reported reduced risk of hip fractures or higher bone BMD in habitual tea drinkers.  This is due to their catechin family of flavonoids.  Alaskan wild-crafted rosehips are loaded with catechins (Hegarty, 2000).

Blueberry prevents bone loss in an OVX rat model.  The objective of this study was to explore the bone protective role of blueberry in an OVX rat model.  The researchers’ findings indicate that blueberry can prevent bone loss as seen by the increase in BMD and favorable changes in biomarkers of bone metabolism (Devareddy, 2008).

An ovariectomized rat (OVX) is a female rat whose ovaries have been removed.  This represents the stages of osteoporosis in humans.  The OVX rat model is the approved preclinical model by the FDA for studying how the decline in endogenous estrogen production by the ovaries at menopause leads to postmenopausal osteoporosis and how potential interventions can preserve bone metabolism in this state (Johnston, 2015).

No. 7 Systemic Booster: contains a higher potency proprietary blend of our pedigreed Bulgarian probiotic bacteria, plus an important fusion of organic whole fruits, berry extracts, chicory root soluble fiber with carefully selected complimentary nutriceuticals (including Vitamin D-3).

“Bone is an organ that the gut has long been known to regulate through absorption of calcium, the key bone mineral. It is clear that modulation of the gut and its microbiome can affect bone density and strength in humans” (McCabe, 2015).

The lactic acid producing bacteria, such as found in the No. 7 Systemic Booster, are known to facilitate the acidification of the GI tract mucus membrane enabling absorption of calcium, magnesium, phosphorous and other important minerals for bone health.

Probiotic organisms produce SCFA as a byproduct of their fermentation of prebiotics such as the inulin, berries, dandelion and other fibers in the Phyto Power and No 7.  Short chain fatty acids (SCFA) can enhance calcium absorption and signal locally in the gut and in the bone in ways that result in decreased osteoclast activity and/or increased osteoblast activity leading to enhanced bone density, structure and strength (McCabe, 2015).

Bibliography

• Bonjour JP. (2005). Dietary protein: an essential nutrient for bone health. J Am Coll Nutr; 24(6 Suppl): 526S-36S.
• Devareddy et al. (2008). Blueberry prevents bone loss in ovariectomized rat model of postmenopausal osteoporosis. JNB; 19(10): 694-699.
• Devirian TA, Volpe SL. (2003). The Physiological Effects of Dietary Boron. Crit Rev in Food Sci and Nut; 43(2): 219-231.
• Heaney RP. (1995). Skeletal development and maintenance: the role of calcium and vitamin D. Adv Endocrinol Metab; 6: 17-38.
• Hegarty VM, May HM, Khaw KT. (2000). Tea drinking and bone mineral density in older women. Am J Clin Nutr; 71: 1003-1007.
• Johnston BD, Ward WE. (2015). The Ovariectomized Rat as a Model for studying Alveolar Bone Loss in Postmenopausal Women. BioMed Research International; 2015: Article ID 635023, 12 pages.
• Laird et al. (2010). Vitamin D and Bone Health: Potential Mechanisms. Nutrients; 2(7): PMC3257670.
• McCabe L., Britton RA., Parameswaran N. (2015). Prebiotic and Probiotic Regulation of Bone Health: Role of the Intestine and its Microbiome. Curr Osteoporos Rep; DOI 10.1007
• Milijkovic N. (2002). Vitamin D. Steroid Hormone Homeostasis and Calcium Fructo-borate Supplementation. Department of Orthopedic Medicine, University of Novi Sad, Novi Sad, Yugoslavia.
• Rao AV, Rao LG. (2007). Carotenoids and human health. Pharmacol Res; 55: 207-216.
• Sacco et al. (2013). Phytonutrients for bone health during ageing. BJCP; 75(3): 697-707.
• Sahni et al. (2009). Protective effect of total carotenoid and lycopene intake on the risk of hip fracture: a 17-year follow-up from the Framingham Osteopororsis Study. J bone Miner Res; 24: 1086-1094.
• Sinnesaelo et al. (2011). Testosterone and the Male Skeleton: A Dual Mode of Action. Journal of Osteoporosis; Article IND 130328: 7 pages.
• Villarea et al. (2000). Effect of DHEA replacement on bone mineral density and body composition in elderly women and men. Clin Endocrinol (Oxf); 53(5): 561-8.

Sincerely yours,

Seann Bardell

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

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