As Ozone levels are increasing, the air we breathe damages our skin and lungs.
Ozone is one of the most toxic of the atmospheric pollutants. It causes our innate immune system to continually overreact (via the activation of the inflammasome) generating chronic inflammation that damages our respiratory mucus membranes and the cells of our skin.
Inflammasome has been correlated with the development of different conditions: atherosclerosis, autoinflammatory disease, Parkinson’s and Alzheimer’s disease, and recently also with skin diseases such as vitiligo, atopic dermatitis, acne, melanoma, pigmentation, and psoriasis (Pambianchi et al., 2020).
One to Two Blueberry Extract capsules a day is shown to prevent inflammasome activation by Ozone.
The BioImmersion Blueberry Extract is a very serious product. Each capsule contains 500mg of this precious extract, equivalent to one and a quarter cups of blueberries. In fact, it takes 80 lbs. of blueberries to get 1 lb. of this extract!
Recommended dose: 1-2 capsules daily.
- Pambianchi, E., Ferrara, F., Pecorelli, A., Woodby, B., Grace, M., Therrien, J. P., ... & Valacchi, G. (2020). Blueberry Extracts as a Novel Approach to Prevent Ozone-Induced Cutaneous Inflammasome Activation. Oxidative Medicine and Cellular Longevity, 2020.
- Wang, H., Liu, J., Pang, D., Li, T., & Liu, R. H. (2019). Mechanisms underlying the protective effects of blueberry extract against ultraviolet radiation in a skin cell co-culture system. Journal of Functional Foods, 52, 603-610.
We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.
Mary Ann Lila is the Director of The Plants For Health Institute at North Carolina State University. She is one of the seminal researchers in the use of blueberries, for human health. Dr. Lila and Giuseppe Valacchi equally supervised the above sited research.
The cutaneous interaction with tropospheric O3 induced an increase in oxidative stress mediators (ROS) and a consequent induction of the inflammasome-related proteins NLRP1 and Caspase 1 that will lead to the assemble of the inflammasome scaffold and the activations of the inflammasome machinery. Blueberry extract (BB) treatment is able to prevent the inflammasome activation by O3.
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