Original Synbiotic- a Daily Defense against a Toxic World

Dear Doctor

We live in an increasingly toxic world with novel and old virulent pathogens.  Your patients’ defense system must be ready and able to protecting their health.

High quality probiotics ingested on a regular basis can greatly add to the body's defensive ability.  The Original Synbiotic strains are chosen for their strength, compatibility, safety and their 40 years of proven ability to neutralize food borne pathogens and xenobiotics (pollution, chemicals, drugs, and heavy metals).

The Original's probiotics are researched pedigreed strains of lactic acid bacteria that support the development of a healthy GI tract microbiome.

A healthy gut microbiome is dependent on strong and proven probiotics, such as the Original strains. The Original Synbiotic provides a powerful symbiotic combination of Lactobacillus acidophilus, Streptococcus thermophilus, Lactobacillus plantarum, Lactobacillus rhamnosus, and Bifidobacterium longum.

Suggested Use:  Take one tsp  daily

Research

The contamination of food with aflatoxins is a worldwide problem. Mold mycotoxins compromise the blood-brain barrier and induce neurodegenerative processes. L rhamnosus binds AFB1 in vivo and reduces bio-absorption of the toxin from the gut. L. acidophilus and B. longum neutralize AFB1 and AFM1 by binding mechanisms. S. thermophilus reduces content of ochratoxin A.

Mutagens cause impaired cell function, cell death or cell transformation into cancer cells. L. acidophilus, B. longum, L. rhamnosus, S. thermophilus and L. plantarum neutralize heterocyclic amines and nitrosamines, two of the most common and powerful mutagenic molecules found in our diet.

Verocytotoxin producing E. coli s0157 are emerging food borne pathogens worldwide. B. longum neutralizes this toxin.

Heavy metals are shown to be amongst the worst toxic chemicals. But research also shows the place of probiotics in detoxifying heavy metals.

The food and water we consume are often contaminated with a range of chemicals and heavy metals, such as lead, cadmium, arsenic, chromium and mercury, that are associated with numerous diseases.  Species such as Lactobacillus and Bifidobacterium, present in the mouth, gut, and vagina have the ability to bind and detoxify these metals.

Halttunen et al. (2007) showed that Lactobacillus and Bifidobacterium species can bind lead and cadmium to their cell surface, and hold on to them through defecation.  Singh and Sharma (2010) showed that L. acidophilus was able to bind and remove arsenic from water. Robinson and Tuovinen (1984) demonstrated that L. rhamnosus in yoghurt reduced the bioaccumulation of mercury and arsenic in pregnant women and children.  Shrivastava et al. (2003) showed that lactobacilli can transform chromium (CrVI) to its less toxic form (CrIII).

The collective ability of the Original probiotic organisms to protect the frontline border of our GI tract membrane from the aggressive enterovirulent pathoges is accomplished via: the production of bactercins, creation of an acid barrier, stimulation of the cell mediated immune system, and protective colonization of enterocytes.

Cani et al. (2008) found that a high animal fat diet changes the GI tract microbiome into a population of increasing numbers of Gram-negative bacteria, which raises the level of LPS endotoxins within the gut lumen and allows their passing through the GI tract membrane into the plasma.

The research team concluded that the plasma concentration of lipopolysaccharides (LPS) controls the inflammatory tone of the body.  This means that high concentrations of LPS set the stage for endotoxemia, resulting in metabolic diseases (obesity, diabetes, CVD) and cancer.  The Original strain of lactic acid bacteria reduce the levels of gram negative bacteria in the gut and support the tightening of a leaky GI tract membrane.

The Original Synbiotic is a collection of pedigreed strains of 5 lactic acid bacteria that help our body shore up its defenses against pathogenic bacteria, virus, molds, heavy metals and much more.

References

• Arena, M. P., Silvain, A., Normanno, G., Grieco, F., Drider, D., Spano, G., & Fiocco, D. (2016). Use of Lactobacillus plantarum strains as a bio-control strategy against food-borne pathogenic microorganisms. Frontiers in Microbiology, 7, 464.
• Cani et al. (2008). Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat induced obesity and diabetes in mice, Diabetes; 57:1470-8.
• Gratz, S., Wu, Q. K., El-Nezami, H., Juvonen, R. O., Mykkänen, H., & Turner, P. C. (2007). Lactobacillus rhamnosus strain GG reduces aflatoxin B1 transport, metabolism, and toxicity in Caco-2 cells. Applied and environmental microbiology, 73(12), 3958-3964.
• Halttunen et al. (2007) Rapid removal of lead and cadmium from water by specific lactic acid bacteria. Int. J. Food Microbiol; 114:30-35.
• Monchese et al. (2012) Bioremediation and Tolerance of Humans to Heavy Metals through Microbial Processes: a Potential Role for Probiotic? AEM;78:6397-6404
• Robinson JB, Tuovinen OH. (1984) Mechanisms of microbial resistance and detoxification of mercury and organomercury compounds: physiological, biochemical, and genetic analyses. Microbiol. Rev.; 48:95-124.
• Shrivastava et al. (2003) Various cells of the immune system and intestine differ in their capacity to reduce hexavalent chromium. FEMS Immunol. Med. Microbiol;38:65-70.
• Singh et al. (2010). Removal of arsenic (III) from waste water using Lactobacillus acidophilus. Bioremediat. J.;14:92-97.

Seann

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

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