High ORAC: The Importance of Measured Polyphenols

The High ORAC Synbiotic - is a measured polyphenol product, we know exactly the potency of the product - 40,000 units of Total ORAC.

Why is this important?

Free radicals are discussed more frequently in the scientific literature, and for good reason (Kozłowska et al., 2021).

We have known that free radicals are involved in many diseases (Bonnefoy et al., 2002), but the research is accumulating faster and the call for polyphenols for anti-oxidant power is growing.

Oxidative stress from free radicals, as Leyane et al. (2021) explains, causes all sorts of diseases, from Alzheimer's to autoimmune, diabetes, cancer and even skin aging, as in wrinkles (Nakai et al., 2021). The list is long. 

This is one reason we have designed and brought to the Therapeutic Foods line a very intense product such as the High ORAC Synbiotic. It's ability to be a good scavenger of these free radicals is important. 

Abstract

Ageing and chronic degenerative pathologies demonstrate the shared characteristics of high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent inflammation, glycation, and mitochondrial abnormalities. Excessive ROS production results in nucleic acid and protein destruction, thereby altering the cellular structure and functional outcome. To stabilise increased ROS production and modulate oxidative stress, the human body produces antioxidants, “free radical scavengers”, that inhibit or delay cell damage. Reinforcing the antioxidant defence system and/or counteracting the deleterious repercussions of immoderate reactive oxygen and nitrogen species (RONS) is critical and may curb the progression of ageing and chronic degenerative syndromes. Various therapeutic methods for ROS and oxidative stress reduction have been developed. However, scientific investigations are required to assess their efficacy. In this review, we summarise the interconnected mechanism of oxidative stress and chronic inflammation that contributes to ageing and chronic degenerative pathologies, including neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), cardiovascular diseases CVD, diabetes mellitus (DM), and chronic kidney disease (CKD). We also highlight potential counteractive measures to combat ageing and chronic degenerative diseases. View Full-Text

 High ORAC Synbiotic

 High ORAC Synbiotic

Polyphenols with a very high Total ORAC and probiotics:  1 capsule a day. We also suggest the High ORAC for post antibiotic care, precisely because of its antimicrobial potential.   

References

• Arcusa, R., Carrillo, J. Á., Xandri-Martínez, R., Cerdá, B., Villano, D., Marhuenda, J., & Zafrilla, M. P. (2021). Effects of a Fruit and Vegetable-Based Nutraceutical on Biomarkers of Inflammation and Oxidative Status in the Plasma of a Healthy Population: A Placebo-Controlled, Double-Blind, and Randomized Clinical Trial. Molecules, 26(12), 3604. Article
• Banerjee, A., & Dhar, P. (2019). Amalgamation of polyphenols and probiotics induce health promotion. Critical reviews in food science and nutrition, 59(18), 2903-2926. Abstract 
• Bonnefoy, M., Drai, J., & Kostka, T. (2002). Antioxidants to slow aging, facts and perspectives. Presse Medicale (Paris, France: 1983), 31(25), 1174-1184.
• Kozłowska, A., & Dzierżanowski, T. (2021). Targeting inflammation by anthocyanins as the novel therapeutic potential for chronic diseases: An update. Molecules, 26(14), 4380.
• Leyane, T. S., Jere, S. W., & Houreld, N. N. (2022). Oxidative Stress in Ageing and Chronic Degenerative Pathologies: Molecular Mechanisms Involved in Counteracting Oxidative Stress and Chronic Inflammation. International Journal of Molecular Sciences, 23(13), 7273.
• Nakai, K., & Tsuruta, D. (2021). What are reactive oxygen species, free radicals, and oxidative stress in skin diseases?. International Journal of Molecular Sciences, 22(19), 10799. 

Sincerely yours,

Dohrea 

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

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