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Chromium and Depression: The Well Being Mineral

Yes! Chromium is back on the shelf, and is packed with so much goodness.

Research on Chromium and Depression have been going on since early 1994 (McCarthy, 1994). In 2015, Brownley et al. suggested to use chromium supplementation for the treatment of diabetes and depression, including bing eating. 

Preventing chronically high blood sugar levels is key to reducing the risk of developing Dementia, Alzheimer’s diseases, anxiety, and depression, all of which are germinated by high blood sugar levels. Chromium is essential for a feeling of well-being.  


Neuropsychiatric disorders and type 2 diabetes (T2D) are major public health concerns proposed to be intimately connected. T2D is associated with increased risk of dementia, neuropsychiatric and mood disorders. Evidences of the involvement of insulin signaling on brain mechanisms related to depression indicate that insulin resistance, a hallmark of type 2 diabetes, could develop in the brains of depressive patients. In this article, we briefly review possible molecular mechanisms associating defective brain insulin signaling with reward system, neurogenesis, synaptic plasticity and hypothalamic-pituitary-adrenal (HPA) stress axis in depression. We further discuss the involvement of tumor necrosis factor α (TNFα) promoting defective insulin signaling and depressive-like behavior in rodent models. Finally, due to the high resistant rate of anti-depressants, novel insights into the link between insulin resistance and depression may advance the development of alternative treatments for this disease. Full-Article

Chromium with High Active Beet Root 

Chromium with High Active Beet Root  

Suggested use: 1 capsule daily

Sincerely yours,



  • Brownley, K. A., Boettiger, C. A., Young, L., & Cefalu, W. T. (2015). Dietary chromium supplementation for targeted treatment of diabetes patients with comorbid depression and binge eating. Medical hypotheses, 85(1), 45-48.
  • Lyra e Silva, N. D. M., Lam, M. P., Soares, C. N., Munoz, D. P., Milev, R., & De Felice, F. G. (2019). Insulin resistance as a shared pathogenic mechanism between depression and type 2 diabetes. Frontiers in psychiatry10, 57.
  • McCarty, M. F. (1994). Enhancing central and peripheral insulin activity as a strategy for the treatment of endogenous depression—an adjuvant role for chromium picolinate?. Medical hypotheses, 43(4), 247-252.

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

Green Facts:

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Chromium Treatment of Depression

McLeod, M. N., & Golden, R. N. (2000). Chromium treatment of depression. International Journal of Neuropsychopharmacology, 3(4), 311-314.






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