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New: 7-Keto DHEA and Weight Loss

There is a body of research on 3-acetyl-7-oxo dehydroepiandrosterone, or 7-Keto DHEA, that presents a great benefit for weight loss. 

And there is also history to this body of research. For example, Kaiman et al. in 2000, created a double-blind, placebo-controlled protocol for 30 adults (28 women and 2 men) that were overweight. They were randomly divided into two groups, one received the 7-oxo-DHEA, 100mg twice daily, and the 2nd group received a placebo. All of them exercised 3 times a week (part of the protocol) for 60 minutes, and under supervision. They also followed a specific diet supervised by a registered dietitian. 

As you can see, this was quite a strict protocol, and indeed 7 dropped out, but 23 completed the 8-week study (which is good!). 

Group 1 lost quite a bit of weight, compared to group 2, and significant reduction in body fat, 3.1 times that of the placebo group (group 2). 

More good news - significant changes in vital signs, blood sugar, hormonal, and renal function. That is exciting. 

And 23 years later, 7-Keto DHEA, a review by Jeyaprakash, et al. (2023) shows that more research is needed (always, after all, we do love to explore), while many scientists speak favorably on 7-Keto and weight loss, these scientists excluded too many studies. As usual, I chose an interesting review article, from scientists that possibly go a bit far in their exclusion criteria, and possibly, because they do not understand the holistic nature of health - they miss out on good research by other scientists. 


 7-Keto DHEA


Yours as always,



  • Jeyaprakash, N., Maeder, S., Janka, H., & Stute, P. (2023). A systematic review of the impact of 7-keto-DHEA on body weight. Archives of gynecology and obstetrics308(3), 777-785. Article
  • Kaiman, D. S., Colker, C. M., Swain, M. A., Torina, G. C., & Shi, Q. (2000). A randomized, double-blind, placebo-controlled study of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy overweight adults. Current therapeutic research, 61(7), 435-442. Abstract

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    My Research: Peace 

    Globe_Home 3One of the most touching elements in Kant's writings is his realization that every human being must be equally honored. He attributes this 'awakening' as he called it, to Rousseau's writing. Letting go of judgements, prejudices, and replace it with honor takes work, it is after all, an awakening awareness that needs reinforcement by remembering continually that even that person that irritates us to no end - deserves to be honored.  This is the beginning of the Categorical Imperative of 'there shall be no war'. 

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