When our brain no longer functions our whole world collapses. Can Blueberries really help?
This new 2022 study by Krikorian et al. is very hopeful and the results are promising! The study investigated the protective effect of blueberries against dementia.
The participants were chosen because of they were 'insulin resistant', overweight and between the ages of 50-65 who had the beginning of cognitive decline. The randomized, double blind, placebo controlled study went on for 12 weeks. This means that in three months participants felt a difference in their cognitive and memory abilities.
The study is well done, and you will enjoy learning about the process and design of a good clinical trial. The results were significant.
Late-life dementia typically develops over a period of many years beginning in midlife. Prevalence of metabolic disturbance also accelerates in middle age and is a prominent risk factor for dementia. Preliminary studies indicate that blueberry supplementation can improve cognitive performance and influence metabolism and brain function and therefore may have a role in early intervention to prevent neurodegeneration. In a randomized controlled trial, we investigated the effects of daily blueberry supplementation in a middle-aged sample of insulin-resistant participants with elevated risk for future dementia. We enrolled overweight men and women, aged 50 to 65 years, with subjective cognitive decline (SCD) and performed pre- and post-intervention assessments of cognition and metabolism and exploratory measures of peripheral mitochondrial function. We observed improved performances for the blueberry group on measures of lexical access, p = 0.003, and memory interference, p = 0.04, and blueberry-treated participants reported reduced memory encoding difficulty in daily life activities, p = 0.03. The blueberry-treated group also exhibited correction of peripheral hyperinsulinemia, p = 0.04, and a modest trend for increased mitochondrial uncoupling, p = 0.11. The cognitive findings indicated improved executive ability in this middle-aged sample. In addition, the changes in metabolic and bioenergetic measures imply potential mechanistic factors associated with anthocyanin and proanthocyanidin actions. The demonstration of these benefits in middle-aged individuals with insulin resistance and SCD suggests that ongoing blueberry supplementation may contribute to protection against cognitive decline when implemented early in at-risk individuals. View Full-Text
Blueberry Extract has a cup and quarter of blueberries that are concentrated. The trial used half a cup. We suggest alternating with the Photo Power.
The Photo Power has Four species of blueberries from the wilds of Alaska! It has a 'handful' of blueberries. We suggest 2 capsules a day.
Krikorian, R., Skelton, M. R., Summer, S. S., Shidler, M. D., & Sullivan, P. G. (2022). Blueberry Supplementation in Midlife for Dementia Risk Reduction. Nutrients, 14(8), 1619. Article
We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.
Rossnagel, K., & Willich, S. N. (2001). Value of complementary medicine exemplified by rose-hips. Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)), 63(6), 412-416.
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