The Original Synbiotic: A Probiotic for the Whole Family is a foundational probiotic that is gentle enough for children and a powerhouse for adults. The probiotic strains were chosen carefully for this purpose - to offer a daily dose of health supporting organisms for the whole family.
With 20 billion cfu/tsp of certified strains of pedigreed probiotic the formula has L. acidophilus, B. longum, L. rhamnosus, L. plantarum, S. thermophilus and 4 grams of inulin derived from organic chicory fiber. Advanced freeze-drying technology. 120 grams/bottle. 4 grams/ tsp. Dairy free. Soy free. Gluten free. No excipients.
- Microbiome Technology creates hardy and viable pedigreed strains of L. acidophilus, B. longum, L. rhamnosus, L. plantarum, S. thermophilus.
- Original strains of lactic acid bacteria are based on ATCC prototypical strains and confirmed routinely by 16sRNA sequencing to provide highest quality probiotic material.
- The Original Strains are chosen for their strength, compatibility, safety and their 40 years of proven ability to neutralize food borne pathogens and xenobiotics.
- Strains selected to protect, counteract and neutralize dietary toxins, mutagens, carcinogens and infectious organisms.
- The contamination of food with aflatoxins is a worldwide problem. Mold mycotoxins compromise the blood-brain barrier and induce neurodegenerative processes. L rhamnosus binds AFB1 in vivo and reduces bio-absorption of the toxin from the gut. L. acidophilus and B. longum neutralize AFB1 and AFM1 by binding mechanisms. S. thermophilus reduces content of ochratoxin A.
- Mutagens cause impaired cell function, cell death or cell transformation into cancer cells. L. acidophilus, B. longum, L. rhamnosus, S. thermophilus and L. plantarum neutralize heterocyclic amines and nitrosamines, two of the most common and powerful mutagenic molecules found in our diet.
- Our home is a global environment. Infectious organisms come from all corners of the world.
- Verocytotoxin producing E. coli s0157 are emerging food borne pathogens worldwide. B. longumneutralizes this toxin.
- The collective ability of the Original probiotic organisms to protect the frontline border of our GI tract membrane from the aggressive enterovirulent pathoges is accomplished via: the production of bactercins, creation of an acid barrier, stimulation of the cell mediated immune system and protective colonization of enterocytes.
- The lactic acid bacterial strains in the Original Synbiotic Formula have demonstrated the ability to inhibit the formation of precancerous colon lesions. Numerous trials performed validate findings.
- Pure inulin, derived from chicory fiber, provides support as a Therapeutic Foods carrier and prebiotic. Provides an ideal food source for the lactic acid organisms to grow, thrive and to protect.
- In the process of fermentation, inulin produces butyric acid and therefore:
- Corrects GI permeability- establishes tight junctions.
- Inhibits colon cancer: stimulating the differentiation of stem cells.
- Improves habit of bowel regularity
- No fillers, flowing agents or excipients of any kind.
Babies and Young Children’s Microbiome
- Amenyogbe, N., Kollmann, T. R., & Ben-Othman, R. (2017). Early-life host–microbiome interphase: the key frontier for immune development. Frontiers in pediatrics, 5, 111. DOI:10.3389/fped.2017.00111
- Cox, M. J., Huang, Y. J., Fujimura, K. E., Liu, J. T., McKean, M., Boushey, H. A., ... & Lynch, S. V. (2010). Lactobacillus casei abundance is associated with profound shifts in the infant gut microbiome. PLoS One, 5(1), e8745. Article
- Goldenberg, J. Z., Lytvyn, L., Steurich, J., Parkin, P., Mahant, S., & Johnston, B. C. (2015). Probiotics for the prevention of pediatric antibiotic‐associated diarrhea. The Cochrane Library. Abstract
- Hodzic, Z., Bolock, A. M., & Good, M. (2017). The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis. Frontiers in pediatrics, 5, 40.Article
- Wegh, C. A., Schoterman, M. H., Vaughan, E. E., Belzer, C., & Benninga, M. A. (2017). The effect of fiber and prebiotics on children’s gastrointestinal disorders and microbiome. Expert review of gastroenterology & hepatology, 11(11), 1031-1045. https://doi.org/10.1080/17474124.2017.1359539
- Bron, P. A., Kleerebezem, M., Brummer, R. J., Cani, P. D., Mercenier, A., MacDonald, T. T., ... & Wells, J. M. (2017). Can probiotics modulate human disease by impacting intestinal barrier function?. British Journal of Nutrition, 117(1), 93-107. Abstract
- Cani PD, Delzenne NM. (2011).The gut microbiome as therapeutic target. Pharmacol Ther, 130(2), 202-12.DOI: 10.1016/j.pharmthera.2011.01.012
- Choudhury, T. G., & Kamilya, D. (2018). Paraprobiotics: an aquaculture perspective. Reviews in Aquaculture. Abstract
- Dimidi, E., Christodoulides, S., Scott, S. M., & Whelan, K. (2017). Mechanisms of action of probiotics and the gastrointestinal microbiota on gut motility and constipation. Advances in Nutrition, 8(3), 484-494. Article
- Martini, E., Krug, S. M., Siegmund, B., Neurath, M. F., & Becker, C. (2017). Mend your fences: the epithelial barrier and its relationship with mucosal immunity in inflammatory bowel disease. Cellular and Molecular Gastroenterology and Hepatology, 4(1), 33-46. Article
- Patel, R., & DuPont, H. L. (2015). New approaches for bacteriotherapy: prebiotics, new-generation probiotics, and synbiotics. Clinical Infectious Diseases, 60(suppl_2), S108-S121. https://doi.org/10.1093/cid/civ177
- Vitetta, L., Briskey, D., Alford, H., Hall, S., & Coulson S. (2014). Probiotics, prebiotics and the gastrointestinal tract in health and disease. Inflammopharmacology, DOI: 10.1007/s10787-014-0201-4. Article
To your health,
We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.