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Fructo Borate for Bone and Heart Health

Dear Friends,

Fructo Borate is a very exciting product: it naturally duplicates the molecular structure of boron as it is found of food—in nature, Boron is always bound to carbohydrate.

In studies, one to two capsules of Fructo Borate have been shown to help prevent and slow down osteoporosis, reduce the inflammation in osteoarthritis, and selectively increase steroid hormones in the blood—testosterone, DHEA and Vitamin D3   level.

Fructo Borate also supports healthy heart by reducing C-reactive protein (CRP) levels.

CRP has been known to be an important marker for the potential of Cardiovascular Disease or CVD (Ridker et al., 2000; Li et al., 2019).


In 2000, the researchers of Ridker et al. conducted a prospective control study among 28,263 apparently healthy postmenopausal women over a mean follow-up period of three years to assess the risk of cardiovascular events associated with base-line levels of markers of inflammation.  Of the 12 makers measure CRP was the strongest univariate predictor of the risk of cardiovascular events.

What is the evidence that Fructo Borate support reduction of C-reactive protein levels?

In 2013, the objective of Militaru et al.’s study was to evaluate the effects of short-term (60-d) oral supplementation with fructo borate, resveratrol , and their combination with stable angina patients.  There was a significant decrease of high-sensitivity C-reactive protein in all groups.  This decrease was greater (39.7% at 60 d) in the Fructo Borate alone group, followed by the resveratrol plus fructo borate group (30.3% at 60 d).

As you can see from ongoing research studies in the references, the Fructo Borate by itself has demonstrable health benefits. Boron is critical for the proper functioning of many important metabolic pathways. The problem is the top soil in many areas of the world is depleted in boron which means that the crops produced from such soil will be deplete in boron.  Supplementing with a boron supplement such as the Fructo Borate makes sense.


  • Christen, T., Trompet, S., Rensen, P. C. N., van Dijk, K. W., Lamb, H. J., Jukema, J. W., ... & de Mutsert, R. (2019). The role of inflammation in the association between overall and visceral adiposity and subclinical atherosclerosis. Nutrition, Metabolism and Cardiovascular Diseases, 29(7), 728-735.

  • Donoiu, I., Militaru, C., Obleagă, O., Hunter, J. M., Neamţu, J., Biţă, A., ... & Rogoveanu, O. C. (2018). Effects of boron-containing compounds on cardiovascular disease risk factors–a review. Journal of Trace Elements in Medicine and Biology, 50, 47-56.

  • Kim, J. K., Chung, Y. T., Kim, H. Y., Han, J. A., & Kim, J. W. (2020). The Factors Associated with High-Sensitivity C-Reactive Protein in Postmenopausal Women: Based on Korea National Health and Nutrition Examination Survey 2016–2017. Korean Journal of Family Practice, 10(2), 96-102.

  • Li, Q., Dai, Z., Cao, Y., & Wang, L. (2019). Association of C‐reactive protein and vitamin D deficiency with cardiovascular disease: A nationwide cross‐sectional study from National Health and Nutrition Examination Survey 2007 to 2008. Clinical cardiology, 42(7), 663-669.

  • Militaru, C., Donoiu, I., Craciun, A., Scorei, I. D., Bulearca, A. M., & Scorei, R. I. (2013). Oral resveratrol and calcium fructoborate supplementation in subjects with stable angina pectoris: effects on lipid profiles, inflammation markers, and quality of life. Nutrition, 29(1), 178-183.

  • Mogoşanu, George Dan, Andrei Biţă, Ludovic Everard Bejenaru, Cornelia Bejenaru, Octavian Croitoru, Gabriela Rău, Otilia-Constantina Rogoveanu et al. "Calcium fructoborate for bone and cardiovascular health." Biological trace element research 172, no. 2 (2016): 277-281.

  • Slavish, D. C., Jones, D. R., Smyth, J. M., Engeland, C. G., Song, S., McCormick, N. M., & Graham-Engeland, J. E. (2020). Positive and negative affect and salivary markers of inflammation among young adults. International journal of behavioral medicine, 27(3), 282-293.

  • Ridker, P. M., Hennekens, C. H., Buring, J. E., & Rifai, N. (2000). C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. New England journal of medicine, 342(12), 836-843.

  • Rogoveanu, O. C., Mogoşanu, G. D., Bejenaru, C., Bejenaru, L. E., Croitoru, O., Neamţu, J., ... & Scorei, R. I. (2015). Effects of calcium fructoborate on levels of C-reactive protein, total cholesterol, low-density lipoprotein, triglycerides, IL-1β, IL-6, and MCP-1: a double-blind, placebo-controlled clinical study. Biological trace element research, 163(1-2), 124-131.

  • Rondanelli, M., Faliva, M. A., Peroni, G., Infantino, V., Gasparri, C., Iannello, G., ... & Tartara, A. (2020). Pivotal role of boron supplementation on bone health: a narrative review. Journal of Trace Elements in Medicine and Biology, 126577.


    Sincerely yours,


    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

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