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Sulforaphane: Multi-Faceted Neuroprotective Effect

There is a great deal of research on the effect of Cruciferous veggies and their Sulforaphanes on detoxification, immune modulation, and anti-oxidation.

Studies are showing positive results of sulforaphens on different kinds of cancers, obesity, skin conditions and more.

Recently though, there is also a growing focus on the nervous system and brain and the ability of Sulforaphanes to offer protection against various neurological diseases including Alzheimer's disease (Kim, 2021). 


Sulforaphane, a potent dietary bioactive agent obtainable from cruciferous vegetables, has been extensively studied for its effects in disease prevention and therapy. Sulforaphane potently induces transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated expression of detoxification, anti-oxidation, and immune system-modulating enzymes, and possibly acts as an anti-carcinogenic agent. Several clinical trials are in progress to study the effect of diverse types of cruciferous vegetables and sulforaphane on prostate cancer, breast cancer, lung cancer, atopic asthmatics, skin aging, dermatitis, obesity, etc. Recently, the protective effects of sulforaphane on brain health were also considerably studied, where the studies have further extended to several neurological diseases, including Alzheimer’s disease (AD), Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, multiple sclerosis, autism spectrum disorder, and schizophrenia. Animal and cell studies that employ sulforaphane against memory impairment and AD-related pre-clinical biomarkers on amyloid-β, tau, inflammation, oxidative stress, and neurodegeneration are summarized, and plausible neuroprotective mechanisms of sulforaphane to help prevent AD are discussed. The increase in pre-clinical evidences consistently suggests that sulforaphane has a multi-faceted neuroprotective effect on AD pathophysiology. The anti-AD-like evidence of sulforaphane seen in cells and animals indicates the need to pursue sulforaphane research for relevant biomarkers in AD pre-symptomatic populations. Article


Glucosinolates & Sulforaphanes  

Glucosinolates & Sulforaphanes  

Each of our vegan capsule has 500 mg of organic broccoli sprouts, harvested at the peak of their phytonutrient power. 



  • Kim, J. (2021). Pre-clinical neuroprotective evidences and plausible mechanisms of sulforaphane in Alzheimer’s Disease. International Journal of Molecular Sciences22(6), 2929. Article

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    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

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     And more on broccoli sprouts:

    Momtazmanesh, S., Amirimoghaddam‐Yazdi, Z., Moghaddam, H. S., Mohammadi, M. R., & Akhondzadeh, S. (2020). Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double‐blind, placebo‐controlled clinical trial. Psychiatry and clinical neurosciences74(7), 398-405. Article



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