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New Research: Degenerative Diseases and Polyphenols

Dear Friend,

Polyphenols are amongst the best micronutrients to prevent degenerative diseases and have been studies for many decades for their health benefits (Quero et al., 2020; Manach et al., 2004).

Quero et al. (2020) review of polyphenols for preventing and easing degenerative diseases, such as cardiovascular, diabetes, neurodegenerative, autoimmune, ophthalmic, and cancer, shows the vast amount of scientific research on polyphenols and how their nutritive abilities lower the risk of these diseases.

Plat based diets and supplements that have potent polyphenols are shown to have many protective health benefits. These micronutrients support the body with their anti-inflammatory and antioxidant abilities as well as “direct interaction or modulation of gene expression” (Quero et al., 2020; Yao et al., 2018).


In recent times, a great number of plants have been studied in order to identify new components with nutraceutical properties, among which are polyphenols. Dietary polyphenols represent a large group of bioactive molecules widely found in food of plant origin and they have been found able to prevent onset and progression of degenerative diseases, as well as reducing and controlling their symptoms. These health protective effects have been mainly related to their antioxidant and anti-inflammatory properties. However, it must be considered that application of isolated polyphenols as nutraceuticals is quite limited due to their poor systemic distribution and relative bioavailability. The present review highlights the potential effect of dietary intervention with polyphenol-rich food and plant extracts in patients with cancer, diabetes and neurodegenerative, autoimmune, cardiovascular and ophthalmic diseases, as well as the possible molecular mechanisms of action suggested in numerous studies with animal models. Article


Phyto Power

Sincerely yours,



  • Fischer, N., Seo, E. J., & Efferth, T. (2018). Prevention from radiation damage by natural products. Phytomedicine47, 192-200.
  • Quero, J., Mármol, I., Cerrada, E., & Rodríguez-Yoldi, M. J. (2020). Insight into the potential application of polyphenol-rich dietary intervention in degenerative disease management. Food & function11(4), 2805-2825. Article
  • Pandey, K. B., & Rizvi, S. I. (2009). Plant polyphenols as dietary antioxidants in human health and disease. Oxidative medicine and cellular longevity2(5), 270-278.
  • Yao, L. H., Jiang, Y. M., Shi, J., Tomas-Barberan, F. A., Datta, N., Singanusong, R., & Chen, S. S. (2004). Flavonoids in food and their health benefits. Plant foods for human nutrition59(3), 113-122.


We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

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