Candidiasis Support

Dear Friends

Did you know that nosocomal infections of multiply resistant pathogens kill more patients each year than breast cancer and HIV combined?  The war on pathogens with antibiotics is not a war that we are winning.  Picking a fight with natural selection is not a smart thing to do (Read, 2012).

The human gut contains a vast ecosystem of microorganisms, a flora that must be ecologically managed well by us, in order to be truly healthy.  The overuse and misuse of antibiotics in medicine, the practice of giving cattle low growth promoting doses of antibiotics has created grave gastrointestinal problems.  There are better ways to manage the ecosystem within our gut and control the overgrowth of pathogens, without antibiotics.

We are proud to have Dr Artemis Morris on our board.  She is a great physician and professor as well. Over the next couple weeks I will present for you her Therapeutic Food protocols to treat Candida/Yeast infections, UTIs, Bacterial Vaginosis, Interstitial Cystitis and Diverticulosis, as well as her protocols for increasing fertility and enhancing neonatal health.  Here is Dr. Morris’s protocol for:

Candida/Yeast Syndrome Support

Candidiasis is the most common opportunistic yeast infection (Martins, 2014).  Candida albicans is an opportunistic pathogen that resides as a harmless commensal in the gut, genitourinary tract and skin (Berman, 2012).

Candida in nonpathogenic concentrations can be protective to the organism against other pathogens and only becomes an opportunistic pathogen when the host has reduced immune competence or an imbalance of the competing bacterial microflora- dysbiosis.

A Therapeutic Food protocol for Candida/Yeast Syndrome:

• Remove the candida by killing the yeast
  1. Garlic, organic– 1-2 capsules TID.
  2. Chlorella– 2-3 BID to TID.
• Crowd out the yeast with commensal organisms that also support the immune system.  Choose from the following probiotic and prebiotic formulas:
  1. Supernatant Synbiotic– 1-2 capsules BID.
  2. Cranberry Pomegranate Synbiotic– 1-2 capsules BID.
  3. Beta Glucan Synbiotic– 1-2 tsp. at night before bed in water.  Use if candida includes gastrointestinal symptoms consistent with a disrupted biofilm and the patient is not sensitive to oats.
  4. Original Synbiotic– 1-2 tsp. daily.
  5. High ORAC Synbiotic– 1-2 capsules BID.
  6. No.7 Systemic Booster– 1-2 tsp. daily.
  7. Be Regular– 1-2 tbs. daily.
• Repair the damage and provide antioxidant support for the immune system and mitochondrial function.
  1. Phyto Power– 2 capsules daily.

Food Science:

Candida is best addressed by supporting the host’s immune function, as well as, decreasing the colony forming units and disrupting the biofilm of the Candida overgrowth.  Anti fungal and antimicrobial treatment frequently results in reoccurrence and there is an increased trend in antimicrobial and antifungal resistant strains of Candida that have been shown to respond well to herbal and natural alternatives.

Garlic– Allicin, a metabolite of raw crushed garlic, is a potent antifungal against Candida species and can be as effective as antifungal drugs.  Allicin blocks lipid synthesis of yeast by inhibiting protein synthesis and hyphae formation of Candida.  A clinical study of garlic supplementation for 2 weeks before the subjects cycle showed a greater self-reported improvement in symptoms compared to the placebo, and non-statistically significant decrease in mean vaginal colony counts after 4 days of supplementation (Watson et al. 2014).

Chlorella addresses toxic body burden that may contribute to Candida overgrowth, promotes probiotic colonization and produces pepsin and chlorophyllase, and stimulates the growth of lactic acid bacteria in promoting optimal digestive health.  An in vitro study (Annamalai, 2015) showed that aqueous self-assembled gold nanoparticles from an aqueous extract of Chlorella vulgaris were antibacterial against Candida albicans and Staphylococcus aurous species.

Probiotics crowd out yeast and pathogenic bacteria as part of their mechanism when taken orally for at least 28 days (Reid, et al. 2003).  Probiotics in combination with antifungals for oral candidiasis improved clinical outcomes and decreased the detection of Candida in saliva compared with antifungals alone (Li et al. 2013).  Probiotics are effective in preventing enteric Candida colonization in preterm neonates; reduced the prevalence of candidaemia and candiduria in critically ill children.  Probiotics reduce colonization of candida by activating mucosal immunity, stimulating cytokine production, IgA secretion, phagocytosis, producing inhibitory substances to pathogens, compete for nutrients with pathogens, inhibit pathogenic attachment, inhibit activity of antimicrobial toxin, have a trophic effect on intestinal mucosa, and modulate innate and adaptive immunity (Kumar, S. 2014).  A clinical study of HIV-positive women by Williams (2000) found that Lactobacillus acidophilus vaginal suppositories taken were as effective as the anti-fungal Clotrimazole at reducing the risk of experiencing a episode of Candida vaginitis.

Cranberry juice extract, high in D-mannose and proanthocyanadins inhibits adherence of E. coli to the uroepithelial cells of the bladder wall and by producing antibacterial hipuric acid; Cranberry extract is antibacterial against Pseudomona aeruginosa, Staphylococcus aureus, and salmonella sp,; antifungal against Candida albicans.  Patel et al. (2011) found Candida glabrata, Candida lusitaniae, Candidia krusei and Cryptococcus neoformans were significantly susceptible to treatment with cranberry proanthocyanidin factions in a broth microdilution assay, with MICs as low as 1 mcg/mL.  Rand et al. (2014) showed cranberry proanthocyanadins reduced biofilm formation of all C. albicans studied and were additive in effect with traditional antifungals.  Feldman (2012) found that cranberry extract inhibited oral candida biofilm formation and adhesion to oral epithelial cells in vitro and inhibited inflammatory cytokines stimulated by candida.  A clinical study by Lee (2010) of women that ingested 900mg of cranberry showed urinary inhibition of E. coli, K. pneumonia, and C. albicans 1-6 hrs after ingestion and 67% of subjects showed urinary inhibition against K. pneumonia on Day 2 of ingestion.

Be Regular supports the elimination of toxins and promotes optimal bowel function.  Be Regular provides prebiotics, promotes commensal probiotic growth, addresses toxin removal, Herxheimer reaction clearing and prevention of re-inoculation with pathogenic bacteria.

Phyto Power provides the provides the antioxidant, antiinflammatory, antimicrobial power of the wildcrafted rosehip (3 species), blueberry (4 species) and dandelion (4 species)- e.g. the antifungal power of rosehip’s high concentration of ellagic acid, the anti C. albicans bioflim powere of the pterostilbene from the blueberry (Li et al., 2014), and the detoxifying ability of the dandelion.

Bibliography:

• Annamalai, J, Nallamuthu, T. (2015). Characterization of biosynthesized gold nanoparticles from aqueous extract of Chlorella vulgaris and their anti-pathogenic properties. Appl Nanosci, 5:603–607.
• Berman, J. (2012). Candida Albicans. Current Biology, 22(16): R620-R622.
• Feldman, M. Tanabe, S., Howell, A, Grenier, D. (2012). Cranberry proanthocyanidins inhibit the adherence properties of Candida albicans and cytokine secretion by oral epithelial cells.  BMC Comp and Alt Med, 12 (6):1-12.
• Kumar, S. (2014). Safety and efficacy of probiotics in Candida colonization and infection: Where do they stand. Mycoses, 57;320.
• Kunal D. Patel, Frank J. Scarano, Miwako Kondo, Robert A. R. Hurta, and Catherine C. Neto (2011). Proanthocyanidin-rich Extracts from Cranberry Fruit (Vaccinium macrocarpon Ait.) Selectively Inhibit the Growth of Human Pathogenic Fungi Candida spp. and Cryptococcus neoformans. Journal of Agricultural and Food Chemistry, 59 (24), 12864-12873.
• Lee, YL, Najm WI, Thrupp, L, Baron, S, SHanbrom, E, Cesario, T. (2010). Anti-microbial Activity of Urine after Ingestion of Cranberry: A Pilot Study. eCAM, 7(2):227-232.
• Li et al. (2014) In Vitro and In Vivo Activities of Pterostilbene against Candida albicans Biofilms. Antimicrobial Agents and Chemotherapy; 58(4):2344-2355.
• Magarinos, HLE, Sahr, C, Selaive, SDC, Costa, ME, FIguerola, FE, Pizarro, OA. (2008).In vitro Inhibitoty Effect of Cranberry (Vqccinium macrocarpum Ait) Juice on Pathogenic Microorganisms. Applied Biochemistry and Microbiology, 44 (3):300–304.
• Martins, N., Ferreira, I. C. F. R., Barros, L., Silva, S., & Henriques, M. (2014). Candidiasis: Predisposing Factors, Prevention, Diagnosis and Alternative Treatment. Mycopathologia, 177(5-6), 223–240. http://doi.org/10.1007/s11046-014-9749-1
• Minich D. M, Bland L. S. (2007). Acid-alkaline balance: role in chronic disease and detoxification. Altern Ther Health Med, 13(4): 62-5.
• Rane, HS, Bernardo, SM, Howell, AB, Lee, SA. (2014). Cranberry-derived proanthocyanidins prevent formation of Candida albicans biofilms in artificial urine through biofilm- and adherence-specific mechanism. J Antimicrob Chemother, 69:428-436.
• Reid, G., Charbonneaus D., Erb, J., Kochanowski, B., Beuerman, D., Poehner, R., Bruce, A.W.  (2003). Oral use of Lactobaccilus Rhamnosis GR-1 and L. fermentum RC-14 significantly alters vaginal flora:A randomized, placebo-controlled trial in 64 healthy women. FEMA Immunology and Medical Microbiology, 35:131-134.
• Watson, CJ, Grando, D, Fairley, CK, Chondros, P, Garland, SM, Myers, SP, Pirotta, M. (2013). The effects of oral garlic on vaginal candida colony counts: a randomised placebo controlled double-blind trial. BJOG, 121:498-506.
• Williams A, Yu C, Tashima K, et al. (2000). Weekly treatment for prophylaxis of Candida vaginitis. Presentation. 7th Conference on Retroviruses and Opportunistic infections. Foundation for Retrovirology and Human Health in collaboration with the (US) National Institute of Allergy and Infectious Diseases and the Centers for Disease Control and Prevention. January 30–February 2.

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please use our products under the advisement of your doctor.

Green Facts: