Blueberry, stem cells, and Ischemic Stroke

An exciting recent study by Jang et al. (2024) discusses the use of Blueberry-treated stem cells as a viable treatment for ischemic stroke.

As we know, ischemic stroke takes place when the blood supply to the brain is restricted or blocked, and there is a lack of oxygen. 

Stem-cells have a powerful regenerative and repair ability, although some, such as  mesenchymal stem cells (MSCs) cannot cross the blood-brain barrier, while others, like Extracellular vesicles (EVs) are found to increase neuronal communication and regeneration. 

This Article is complex and exciting: blueberries infused EVs stem cells as a drug form to treat the brain. 

Scientifically speaking, blueberries are now considered as a true therapeutic food for the brain because of the powerful anti-glycation and neuro-protective effects, increase in memory, motor function ability, and now ischemic strokes (Parrella et al., 2020). 

We have discussed the effects of blueberries for the past two decades, their anti-inflammatory, anti-oxidant, anti-microbial properties, and the need in our world today to protect the body - brain, nervous system - bathing each cell with these life generating polyphenols. 

Enjoy!

 Blueberry Extract

Yours as always,

Dohrea 

References

• Jang, E., Yu, H., Kim, E., Hwang, J., Yoo, J., Choi, J., ... & Jang, S. (2024). The Therapeutic Effects of Blueberry-Treated Stem Cell-Derived Extracellular Vesicles in Ischemic Stroke. International Journal of Molecular Sciences, 25(12), 6362.Article
• Parrella, E., Gussago, C., Porrini, V., Benarese, M., & Pizzi, M. (2020). From preclinical stroke models to humans: Polyphenols in the prevention and treatment of stroke. Nutrients, 13(1), 85.
• Sun, K., Zheng, X., Jin, H., Yu, F., & Zhao, W. (2022). Exosomes as CNS drug delivery tools and their applications. Pharmaceutics, 14(10), 2252.
• Zheng, T., Bielinski, D. F., Fisher, D. R., Zhang, J., & Shukitt-Hale, B. (2022). Protective Effects of a Polyphenol-Rich Blueberry Extract on Adult Human Neural Progenitor Cells. Molecules, 27(19), 6152. Article
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